4 research outputs found

    C2 interpolation of spatial data subject to arc-length constraints using Pythagorean-hodograph quintic splines

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    International audienceIn order to reconstruct spatial curves from discrete electronic sensor data, two alternative C2 Pythagorean-hodograph (PH) quintic spline formulations are proposed, interpolating given spatial data subject to prescribed constraints on the arc length of each spline segment. The first approach is concerned with the interpolation of a sequence of points, while the second addresses the interpolation of derivatives only (without spatial localization). The special structure of PH curves allows the arc-length conditions to be expressed as algebraic constraints on the curve coefficients. The C2 PH quintic splines are thus defined through minimization of a quadratic function subject to quadratic constraints, and a close starting approximation to the desired solution is identified in order to facilitate efficient construction by iterative methods. The C2 PH spline constructions are illustrated by several computed examples

    Passive identification of acoustic propagation media with viscous damping

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    International audienceThis paper concerns passive identification of an acous- tic propagation medium with viscous damping. We propose a Green correlation approach to retrieve time of arrival be- tween two sensors and to retrieve also times of arrival of first echoes. Green correlation is introduced as the cross- correlation of acoustic field generated by a white noise ex- citing the medium. This approach is experimentally vali- dated and compared to the classical method which consists in retrieving the Green function from the Green correlation through a Ward identity. We show that this latter approach appears to be numerically inaccurate and above all unneces- sary in the acoustic case with viscous damping

    A global metagenomic map of urban microbiomes and antimicrobial resistance

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    We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.Funding: the Tri-I Program in Computational Biology and Medicine (CBM) funded by NIH grant 1T32GM083937; GitHub; Philip Blood and the Extreme Science and Engineering Discovery Environment (XSEDE), supported by NSF grant number ACI-1548562 and NSF award number ACI-1445606; NASA (NNX14AH50G, NNX17AB26G), the NIH (R01AI151059, R25EB020393, R21AI129851, R35GM138152, U01DA053941); STARR Foundation (I13- 0052); LLS (MCL7001-18, LLS 9238-16, LLS-MCL7001-18); the NSF (1840275); the Bill and Melinda Gates Foundation (OPP1151054); the Alfred P. Sloan Foundation (G-2015-13964); Swiss National Science Foundation grant number 407540_167331; NIH award number UL1TR000457; the US Department of Energy Joint Genome Institute under contract number DE-AC02-05CH11231; the National Energy Research Scientific Computing Center, supported by the Office of Science of the US Department of Energy; Stockholm Health Authority grant SLL 20160933; the Institut Pasteur Korea; an NRF Korea grant (NRF-2014K1A4A7A01074645, 2017M3A9G6068246); the CONICYT Fondecyt Iniciación grants 11140666 and 11160905; Keio University Funds for Individual Research; funds from the Yamagata prefectural government and the city of Tsuruoka; JSPS KAKENHI grant number 20K10436; the bilateral AT-UA collaboration fund (WTZ:UA 02/2019; Ministry of Education and Science of Ukraine, UA:M/84-2019, M/126-2020); Kyiv Academic Univeristy; Ministry of Education and Science of Ukraine project numbers 0118U100290 and 0120U101734; Centro de Excelencia Severo Ochoa 2013–2017; the CERCA Programme / Generalitat de Catalunya; the CRG-Novartis-Africa mobility program 2016; research funds from National Cheng Kung University and the Ministry of Science and Technology; Taiwan (MOST grant number 106-2321-B-006-016); we thank all the volunteers who made sampling NYC possible, Minciencias (project no. 639677758300), CNPq (EDN - 309973/2015-5), the Open Research Fund of Key Laboratory of Advanced Theory and Application in Statistics and Data Science – MOE, ECNU, the Research Grants Council of Hong Kong through project 11215017, National Key RD Project of China (2018YFE0201603), and Shanghai Municipal Science and Technology Major Project (2017SHZDZX01) (L.S.
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